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Synthesis of 9-(2,3-Dideoxy-2,3-Difluoro-β-D- Arabinofuranosyl)Adenine

✍ Scribed by Sivets, Grigorii G.; Kalinichenko, Elena N.; Mikhailopulo, Igor A.


Book ID
121366656
Publisher
Taylor and Francis Group
Year
2007
Tongue
English
Weight
86 KB
Volume
26
Category
Article
ISSN
0732-8311

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A new sugar, methyl 5-O-benzoyl-2,3-dideoxy-2,3-difluoro-D-lyxofuranoside (8), which features fluorine substituents on adjacent carbon positions above the plane of the tetrahydrofuran ring, was synthesized from 1,2: 5,6-di-O-isopropylidine-alpha-D-allofuranose in seven steps and 22% overall yield. D