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Synthesis of 9-[11C]methylamino-1,2,3,4-tetrahydroacridine, a potent acetylcholine esterase inhibitor

โœ Scribed by S. Bonnot; C. Prenant; C. Crouzel


Book ID
103922541
Publisher
Elsevier Science
Year
1991
Weight
230 KB
Volume
42
Category
Article
ISSN
0883-2889

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## Abstract (ยฑ) 3โ€(6โ€Nitroโ€2โ€quinolinyl)โ€[9โ€methylโ€^11^C]โ€3,9โ€diazabicycloโ€[4.2.1]โ€nonane ([^11^Cโ€methyl]NS 4194), a selective serotonin reuptake inhibitor (SSRI), was synthesised within 35 min after end of bombardment with a radiochemical purity >98%. It had a decayโ€corrected radiochemical yield o