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Synthesis of 8,9-leukotriene C3 and D3

✍ Scribed by S.Richard Baker; John R. Boot; Sarah E. Morgan; David J. Osborne; William J. Ross; Patricia R. Shrubsall


Book ID
104219906
Publisher
Elsevier Science
Year
1983
Tongue
French
Weight
192 KB
Volume
24
Category
Article
ISSN
0040-4039

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## Abstract A β€œone pot” reduction of ethyl [1,2‐^13^C~2~]bromoacetate with diisobutylaluminium hydride in dichloromethane, followed by reaction with triphenylphosphine, then triethylamine, yields [1,2‐^13^C~2~]formylmethylenetriphenylphosphorane. Consecutive Wittig reactions of [1,2‐^13^C~2~] formy