Synthesis of 8,8-R,R-8,9-dihydro[1,2,4]triazolo[1,5-a]quinazolin-6(7H)-ones
✍ Scribed by Kh. S. Shikhaliev; D. V. Kryl’skii; A. Yu. Potapov; M. Yu. Krysin
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 290 KB
- Volume
- 54
- Category
- Article
- ISSN
- 1573-9171
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract magnified image 2′‐Substituted 5′,6′,7′,8′‐tetrahydro‐4′__H__‐spiro[cyclohexane‐1,9′‐[1,2,4]triazolo[5,1‐__b__]quinazolines] **3a‐d** were synthesized by condensation of 3‐substituted 5‐amino‐1,2,4‐triazoles **1a‐d** with 2‐cyclohexylidene cyclohexanone **2** in DMF. The compounds **3*
## Abstract __N__‐(2‐Amino‐5,6,7,8‐tetrahydro‐6‐quinazolinyl)acetamide (**9**) and __N__‐(2,4‐diamino‐5,6,7,8‐tetrahydro‐6‐quinazolinyl)acetamide (**6**) were synthesized from __N__‐(4‐oxocyclohexyl)acetamide (**5**) as novel peptidomimetic building blocks. With similar purpose, __N__‐(6‐oxo‐5,6,7,