✦ LIBER ✦
Synthesis of 8-O-alkylshikonin(alkannin)s: new ketal formation, tautomerism, and nucleophilic aromatic substitution
✍ Scribed by Tsutomu Tsuchiya; Shintaro Ohmuro
- Book ID
- 104232240
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 97 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The reaction of 5,8,1%-tri-O-acetylshikonin(alkannin) with KOH in an alcohol gives selectively 1%-O-acetyl-8-O-alkylshikonin(alkannin)s through methoxylation under tautomerism followed by quinone monoketalization.