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Synthesis of [8-14C]. N6-(Δ2-isopentenyl ) adenosine

✍ Scribed by M. H. Fleysher


Publisher
John Wiley and Sons
Year
1972
Tongue
French
Weight
248 KB
Volume
8
Category
Article
ISSN
0022-2135

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Separation of the Δ2 and Δ3 isomers of N
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Since the first report on the presence of the modified nucleoside N6-(A'-isopentenyl) adenosine (A~-IPA) in yeast tRNA (1,2) several other nucleosides with related structures have been isolated and characterized from tRNA's of various species (3,4). All these compounds have been shown to possess po

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## Abstract 6‐n‐Propyl‐2‐thiouracil‐6−^14^C was prepared from sodium butyrate‐1−^14^C, with a radiochemical yield of 34%. Butyryl chloride‐1−^14^C was prepared from butyric acid‐1−^14^C and condensed with sodio ethylacetoacetate to yield ethyl β‐oxohexanoate‐β−^14^C. The β‐keto ester was condensed