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Synthesis of 7α- and 7β-Spermidinylcholesterol, Squalamine Analogues.

✍ Scribed by B. Choucair; M. Dherbomez; C. Roussakis; L. El Kihel

Publisher
John Wiley and Sons
Year
2004
Weight
30 KB
Volume
35
Category
Article
ISSN
0931-7597

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## Summan: The title compounds have been prepared in a highly eficientfashion by a synthetic route involving an intramolecular Diels-Alder reaction of an acetylenic thiazole followed by reductive modification of the resulting fused-ring thiophene. 13. Models indicate that the difference in selecti