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Synthesis of 7-Sulfamoyl-Substituted 2-Oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepines.

โœ Scribed by Mikhail V. Dorogov; Sergey A. Ivanovsky; Maria Y. Khakhina; Dmitry V. Kravchenko; Sergey E. Tkachenko; Alexandre V. Ivachtchenko


Publisher
John Wiley and Sons
Year
2007
Weight
26 KB
Volume
38
Category
Article
ISSN
0931-7597

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Practical stereoselective synthesis of (
โœ Tomoichi Shinohara; Kazumi Kondo; Hidenori Ogawa; Toyoki Mori; Kyoko Nozaki; Tam ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 134 KB ๐Ÿ‘ 1 views

Highly enantioselective asymmetric hydrogenation of readily accessible olefins, (E)- and (Z)-[1-(toluene-4-sulfonyl)-1,2,3, 4-tetrahydro-1H-benzo[b]azepin-5-ylidene]acetic acid (4a and 4b, respectively) and [1-(toluene-4-sulfonyl)-2, 3-dihydro-1H-benzo[b]azepin-5-yl]acetic acid (4c), is presented as