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Synthesis of 7-(alkenyl, cycloalkenyl, and 1,2,3,6-tetrahydro-4-pyridinyl)quinolones

✍ Scribed by John S. Kiely; Edgardo Laborde; Lawrence E. Lesheski; Ruth A. Bucsh

Book ID
112130138
Publisher
Journal of Heterocyclic Chemistry
Year
1991
Tongue
English
Weight
361 KB
Volume
28
Category
Article
ISSN
0022-152X

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An improved synthesis of 1-(1,2,3,6-tetr
An improved synthesis of 1-(1,2,3,6-tetrahydro-1-methyl-4-pyridinyl)ethanone, isoarecolone
✍ J. Warren Beach πŸ“‚ Article πŸ“… 1997 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 190 KB

## Abstract A convenient synthesis of 1‐(1,2,3,6‐tetrahydro‐1‐methyl‐4‐pyridinyl)ethanone, isoarecolone, starting with 4‐acetylpyridine is presented. 4‐Acetylpyridine was protected as the ketal followed by reaction with iodomethane to give the quaterary salt. The quaterary salt was reduced with sod