Synthesis of 6-substituted imidazo[2,1-b]thiazoles via Pd/Cu-mediated Sonogashira coupling in water

✍ Scribed by Taghi A. Kamali; Mohammad Bakherad; Mahmoud Nasrollahzadeh; Shiva Farhangi; Davood Habibi

• Book ID: 104096773
• Publisher: Elsevier Science
• Year: 2009
• Tongue: French
• Weight: 414 KB
• Volume: 50
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2009.07.017

✦ Synopsis

NMR, IR and mass) data of the 6-substituted imidazo[2,1-b]thiazoles are given below.

6

Table 3, entry 1). 1 H NMR (DMSO-d 6 , 500 MHz): d H 4.25 (s, 2H, CH 2 ), 6.95-7.96 (m, 6H, thiazole, ArH), 8.63 (s, 1H, CH of imidazole); 13 C NMR (DMSO-d 6 , 125 MHz): d C 35.32, 110.46, 122.45, 124.10, 128.93