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Synthesis of 6-O-α-d-glucopyranosylcyclomaltoheptaose

✍ Scribed by Péter Fügedi; Pál Nánási; József Szejtli

Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
650 KB
Volume
175
Category
Article
ISSN
0008-6215

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✦ Synopsis

2,3-Di-O-acetyl)hexakis(2,3,6-tri-O-acetyl)cyclomaltoheptaose was prepared by reaction of cyclomaltoheptaose with tert-butyldimethylsilyl chloride in pyridine followed by acetylation and desilylation. Glycosylation with 2,3,4,6-tetra-o-benzyl-I-0-trichloroacetimidoyl-(Y -D -glucopyranose, using trifluoromethanesulfonic acid as catalyst, and removal of the protecting groups from the product then afforded the title compound. * Dedicated to Professor Rezsd Bog& in the year of his 75th birthday. + Note added in proof: After submission of this manuscript, Dr. Kenichi Takeo informed us in a personal communication that the synthesis of 6-0-cu-D-glucopyranosylcyclomaltohexaose was accomplished by him (J. Curbohydr. Chem., submitted).

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