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Synthesis of 6-[[(hydroxyimino)phenyl]methyl]-1-[(1-methylethyl)sulfonyl]-1H-imidazo[4,5-b]pyridin-2-amine. An aza analogue of enviroxime

✍ Scribed by James L. Kelley; Ed W. Mclean; Ronda G. Davis; Ronald Crouch


Book ID
112129793
Publisher
Journal of Heterocyclic Chemistry
Year
1990
Tongue
English
Weight
298 KB
Volume
27
Category
Article
ISSN
0022-152X

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Synthesis of deuterated 2-amino-1-methyl
✍ Mary J. Tanga; James E. Bupp; Wallace W. Bradford πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 95 KB

## Abstract The syntheses of the deuterium‐labeled food mutagen 2‐amino‐1‐methyl‐6‐phenyl‐1H‐imidazo[4,5‐b]pyridine (PhIP) and its __N__‐hydroxy metabolite are described. Unlabeled PhIP is deuterated using a boron trifluoride phosphoric acid complex in one step. Labeled PhIP–^2^H~5~ is nitrosated t