Synthesis of 6-Hydroxy Derivatives of Steroidal Hormones by SeO2 Mediated Oxidation.
โ Scribed by Rainer Strommer; Claudia Hoedl; Wolfgang Strauss; Reinhard Sailer; Ernst Haslinger; Hans Wolfgang Schramm; Christoph Seger
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 99 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Abstract
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๐ SIMILAR VOLUMES
## Abstract The reaction allows convenient and efficient access to a number of coumestan derivatives which are of biological interest.
Tertiary phosphine oxides are prepared under mild conditions by sequential addition of diphenylphosphinoyl chloride to divalent samarium compounds (SmCp, and SmI,) followed by reaction with various electrophiles such as organic halides, tosylates, epoxides or a,gunsaturated ketones. Biscyclopentadie