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Synthesis of 6-chloro 2(-ethylamino)-4-methyl-4-phenyl-[-4-14C]-4H-3,1-benzoxazine (Etifoxine)

✍ Scribed by Elmostafa Azim; Jean Michel Dupuy; Françis Lepage; Annie Veyre; Jean Claude Madelmont

Publisher
John Wiley and Sons
Year
1997
Tongue
French
Weight
322 KB
Volume
39
Category
Article
ISSN
0022-2135

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## Abstract A new series of 16 6‐chloro‐1,1‐dioxo‐7‐{4‐[(4‐R^1^‐phenyl)imino]‐4__H__‐3,1‐benzoxazin‐2‐yl}‐3‐(substituted amino)‐1,4,2‐benzodithiazines **7–22** was prepared in order to evaluate the cytotoxic activity against six human cancer cell lines. The structures of the new compounds were conf