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Synthesis of 6- and 7-propargyloxy derivatives of 4-(3-fluoroanilino)-quinazoline

✍ Scribed by Helen Trinh Pham; Robert N. Hanson; Sandra L. Olmsted; Anton Kozhushnyan; Adam Visentin; Paul J. Weglinsky; Chris Massero; Kristen Bailey

Book ID
104098657
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
393 KB
Volume
52
Category
Article
ISSN
0040-4039

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✦ Synopsis

The preparation of the novel isomeric 6-and 7-propargyloxy derivatives of 4-(3-fluoroanilino)-quinazoline was achieved using a six-step process. An alternate method to the 7-propargyloxy derivative and analogous 7-propargyloxy containing compounds is also described.

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