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Synthesis of 6-Amino-5-R2-7-(6-R1-4-oxo-3,4-dihydro-2-quinazolyl)-5H-pyrrolo[2,3-b]pyrazine-2,3-dicarbonitriles

✍ Scribed by Yu. M. Volovenko; G. G. Dubinina

Book ID
110336637
Publisher
Springer US
Year
2002
Tongue
English
Weight
159 KB
Volume
38
Category
Article
ISSN
0009-3122

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✍ Kazuko Shirai; Koushi Fukunishi; Dongfeng Hou; Masaru Matsuoka 📂 Article 📅 2000 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 450 KB 👁 1 views

## Abstract Previously synthesized 2‐(3′‐chloro‐5′,6′‐dicyanopyrazin‐2′‐yl)cyclopentan‐1‐one **1**, obtained from the reaction of 2,3‐dichloro‐5,6‐dicyanopyrazine with 1‐pyrrolidino‐1‐cyclopentene, was further reacted with primary alkylamines to give mixtures of diastereomer of 5‐alkyl‐2,3‐dicyano‐