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Synthesis of (5α)-17-azaandrostan-3-ols and (5α)-17-aza-D-homoandrostan-3-ols and their N-acylated derivatives

✍ Scribed by Xin Jiang; Jie Wang; Jiaxin Hu; Zongming Ge; Yuefei Hu; Hongwen Hu; Douglas F Covey

Book ID
117213376
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
192 KB
Volume
66
Category
Article
ISSN
0039-128X

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Novel azaandrostane derivatives for the synthesis of 17β-(N-tert-butyl carbamoyl)-4-aza-5α-androst-1-ene-3-one
✍ Divvela V. N. Srinivasa Rao; Ganala Naga Trinadhachari; Koilpillai Joseph Prabah 📂 Article 📅 2007 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 297 KB

## Abstract magnified image A new industrially viable process for the preparation of 1β‐(__N__‐__tert__‐butyl carbamoyl)‐4‐aza‐5α‐androst‐1‐ene‐3‐one, also known by the generic name finasteride (**6**) from the new azaandrostane derivatives such as 1β‐(__N__‐__tert__‐butyl carbamoyl)‐4‐benzoyl‐4‐a