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Synthesis of 5-(β-D-ribofuranosyl)-1,2,4-oxadiazole-3-carboxamide

✍ Scribed by William J. Hennen; Roland K. Robins


Book ID
112128083
Publisher
Journal of Heterocyclic Chemistry
Year
1985
Tongue
English
Weight
170 KB
Volume
22
Category
Article
ISSN
0022-152X

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Syntheses of [2-2H]-5-ethynyl-1-(β-D-rib
✍ Noriaki Minakawa; Akira Matsuda; Zuping Xia; Leonard I. Wiebe; Edward E. Knaus 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 654 KB

Metallation of 5-ethynyl-1-(2,3,5-tri-O-terf-butyldimethylsilyl-~-~-ribof~anosyl)imidazole-4-carboxamide (1) using n-BuLi, deuteration with deuterium oxide and removal of the fertbutyldimethylsilyl protecting groups using tetrabutylammonium fluroide yielded [2-'H]-5ethynyl-1 -(~-D-ribofi1ranosyl)imi