𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of 5-Substituted-1 H -indol-2-yl-1 H -quinolin-2-ones: A Novel Class of KDR Kinase Inhibitors

✍ Scribed by Kuethe, Jeffrey T.; Wong, Audrey; Qu, Chuanxing; Smitrovich, Jacqueline; Davies, Ian W.; Hughes, David L.


Book ID
120271455
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
273 KB
Volume
70
Category
Article
ISSN
0022-3263

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Synthesis of 1-(1H-Imidazol-2-yl)ethane-
✍ Andreas N. RΓΆhrle; Helmut Schmidhammer πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 German βš– 473 KB

Compounds 6-13 were prepared starting from 1-(triphenlymethy1)-protected 1H-imidazoles 14 and 15 in several steps. Lithiation with BuLi in T H F followed by reaction with (triphcny1methoxy)acetaldehyde (16) afforded 17 and 18, respectively. 0-Methylation of 17 and 18 gave diethers 19 and 20, respect