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Synthesis of 5-substituted 1-aryl-1H-pyrazole-4-acetonitriles, 4-methyl-1-phenyl-1H-pyrazole-3-carbonitriles and pharmacologically active 1-aryl-1H-pyrazole-4-acetic acids

✍ Scribed by Giulia Menozzi; Pietro Schenone; Luisa Mosti; Franceses Mattioli


Book ID
112130711
Publisher
Journal of Heterocyclic Chemistry
Year
1993
Tongue
English
Weight
376 KB
Volume
30
Category
Article
ISSN
0022-152X

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The title compound 3 was obtained during the rearrangement of isoxazol-5-yl hydrazine 1 to 1 -aminopyrazolone 2 at \(115^{\circ}\). X-ray analysis of the corresponding benzylidene derivative allowed us to achieve the structure assignment.