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Synthesis of 5-spirocyclohexyl-2,4-dithiohydantoin derivatives: a potential anti-leishmaniasis agent

✍ Scribed by Abdel-Sattar S. Hamad Elgazwy; Saad R. Atta-Allha; Sherif M. A. S. Keshk


Book ID
106214124
Publisher
Springer Vienna
Year
2008
Tongue
English
Weight
334 KB
Volume
140
Category
Article
ISSN
0026-9247

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## Abstract Using sodium acetate, [1‐^14^C] as a starting material, a total of seven steps were required to synthesize the title compound. This involved acylation of ortho‐dichlorobenzene to form dichloroacetophenone, [2‐^14^C] (I). The 2‐phenyl‐4‐quinoline carboxylic acid, [2‐^14^C] (II) was prepa