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Synthesis of 5-Hydroxymethyl-8-methyl-3-(3-aryl-[1,2,4]oxadiazol-5-yl)-2 H -pyrano[2,3- c ]pyridin-2-ones and Their Esters

✍ Scribed by Zhuravel, Irina O.; Kovalenko, Sergiy M.; Zaremba, Oleg V.; Detistov, Oleksandr S.; Kovalenko, Svitlana S.; Chernykh, Valentin P.


Book ID
120908501
Publisher
Taylor and Francis Group
Year
2008
Tongue
English
Weight
164 KB
Volume
38
Category
Article
ISSN
0039-7911

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Synthesis of substituted 3-(5-amino-[1,3
✍ Irina O. Zhuravel'; Valentin P. Chernykh; Pavlo E. Shinkarenko; Sergiy M. Kovale πŸ“‚ Article πŸ“… 2004 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 222 KB πŸ‘ 1 views

## Abstract An efficient two‐step synthesis of novel 3‐(5‐amino‐[1,3,4]thiadiazol‐2‐yl)‐2__H__‐pyrano[2,3‐__c__]pyridine‐2‐ones was developed. In the first step, a new 2__H__‐pyrano[2,3‐__c__]pyridine‐3‐carboxamide **5** was prepared by Knoevenagel condensation of pyridoxal hydrochloride with cyano