Synthesis of 5-ethylpyrimidine nucleoside analogs

✍ Scribed by Keiko Takenaka; Masako Muraoka; Tadakazu Tsuji

• Book ID: 102346010
• Publisher: Journal of Heterocyclic Chemistry
• Year: 1997
• Tongue: English
• Weight: 365 KB
• Volume: 34
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.5570340254

✦ Synopsis

Abstract

This paper describes the synthesis of acyclic, cyclic, and deoxy sugar nucleosides of 5‐ethylpyrimidine, i.e., i) 1‐(2‐hydroxyethoxymethyl), 1‐(2‐methoxyethoxymethyl), and 1‐ethoxyethyl derivatives of 5‐ethyl‐uracil and 5‐ethylcytosine, ii) 5‐ethyl‐1‐(tetrahydro‐2__H__‐pyran‐2‐yl)‐ and ‐1‐(tetrahydrofuran‐2‐yl)uracils, and iii) 5‐ethyl‐2′‐deoxyuridine.