Abstrat -Treatment of ethyl (heteroalkylidene)aminopyrazole-4-carboxylates with hydrazine hydrate generally provides a ready synthetic route to 5-amino-4,5-dihydropyrazolo [3.4-d] pyrimidin-4-ones, although ethyl 5-[(dimethylamino)alkylidene]aminopyrazole-4-carboxylates are unreactive. On the other
β¦ LIBER β¦
Synthesis of 5-amino-4, 5-dihydropyrazolo [3,4-d] pyrimidin-4-ones and related isomeric systems : Part I. Synthesis and characterization of potential intermediates
β Scribed by A. Maquestiau; J.-J. Vanden Eynde
- Book ID
- 104203022
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- French
- Weight
- 572 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
β¦ Synopsis
Reactions between aminopyrazole-4-carboxylic acids derivatives and orthoesters or amide acetals lead, in most cases, to the introduction of a heteroalkylidene moiety on the amino group of ethyl aminopyrazole-4-carboxylates and on the p-hydrazide nitrogen atom of aminopyrazole-4-carboxhydrazides.
Several factors governing the course of these reactions are discussed.
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