Synthesis of 5-(9-adenyl)-4-ethyl-3-methyl-5(H)-furanone

✍ Scribed by Iris L. Doerr; Robert E. Willette

• Publisher: Elsevier Science
• Year: 1970
• Tongue: French
• Weight: 117 KB
• Volume: 11
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)97797-4

✦ Synopsis

The biological importance of unsaturated la&ones is well known. We wish to report the synthesis of the title compound, a new type of adenine derivative which substitutes an a,i3unsaturated y-lactone for the 9-ribofuranosyl moiety of adenosine. The synthesis proceeded from the known 5-hydroxy-4-ethyl-3-methyl-5(H)-furanone,