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Synthesis of 4-β-D-arabinofuranosyl-5,6-dihydro-2H-1,2,4-thiadiazin-3-one 1,1-dioxide and x-ray diffraction analysis of its 2′,3-anhydro precursor

✍ Scribed by A. C. Schroeder; T. Srikrishnan; R. Parthasarathy; A. Block


Book ID
112126397
Publisher
Journal of Heterocyclic Chemistry
Year
1981
Tongue
English
Weight
359 KB
Volume
18
Category
Article
ISSN
0022-152X

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The reaction of 3-mercapto-4-aryIideneamino-l,2,4triazoles 2b-d, 3a-d with ethyl bromoacetate and/or phenacyl bromide in hot DMF and triethylamine affords the stereochemically pure 7-acyl-6-aryl-6,7dihydro-5H-lt2, 4-triazolo[3,4-b][l, 3,4]thiadiazines