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Synthesis of 4-(trifluoromethyl)pyrido[4,3-d]pyrimidine derivatives

✍ Scribed by L. S. Vasil’ev; S. V. Baranin; A. V. Ignatenko; Yu. V. Nelyubina; V. A. Dorokhov


Book ID
106521702
Publisher
Springer
Year
2010
Tongue
English
Weight
259 KB
Volume
59
Category
Article
ISSN
1573-9171

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Synthesis of Derivatives of Pyrido[4,3-d
✍ Jian-Chao Liu; Hong-Wu He; Qing-Yun Ren; Ming-Wu Ding 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 German ⚖ 93 KB 👁 1 views

A series of new, 2-substituted 3-aryl-8,9,10,11-tetrahydro-5-methyl[1]benzothieno [3',2' : 5,6]pyrido [4,3-d]pyrimidin-4(3H)-ones, compounds 5a -q, were designed and synthesized via the aza-Wittig reaction as the key step. The iminophosphorane 1 reacted with phenyl isocyanate (or 4-chlorophenyl isoc