Synthesis of 4-substituted aminobenzoate quaternary salts as potent antispasmodic agents
โ Scribed by Elsebai A. Ibrahim; Raafat Soliman; Mohamed Gabr
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 351 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0022-3549
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โฆ Synopsis
N-(Diethylaminoethyl)-4-substituted aminobenzoate quaternary salts, N-(diethylaminoethyl)-4-substituted aminobenzamide quaternary salts, 4-substituted acylaminobenzamide quaternary salts, and 4-substituted acylaminosalicylamide derivatives were prepared and tested for antispasmodic activity. Preliminary pharmacological tests on isolated guinea pig ileum revealed that the new compounds possess nonspecific inhibitory action on smooth muscles.
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