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Synthesis of 4-(Methoxycarbonyl)phenyl β-Lactoside Derivatives Modified at C(6) or C(6′), and Evaluation of Their Inhibitory Activity on Erythrina cristagalli Lectin-Mediated Hemagglutination

✍ Scribed by Anna Paola Butera; José Dias de Souza Filho; Maria Auxiliadôra Fontes Prado; Marilda Pereira Lisboa; Ricardo José Alves


Publisher
John Wiley and Sons
Year
2009
Tongue
German
Weight
245 KB
Volume
92
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

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We report herein the synthesis of 4‐(methoxycarbonyl)phenyl β‐lactoside and eight derivatives modified at C(6) or C(6′). These compounds were evaluated in hemagglutination inhibition assay using the lectin from Erythrina cristagalli. None of the compounds showed enhanced activity as compared to lactose.