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Synthesis of 4-Membered Carbasugars by Way of Stereoselective SmI 2 -Mediated Aldehyde–Alkene Cyclization

✍ Scribed by Nocquet, Pierre-Antoine; Hazelard, Damien; Gruntz, Guillaume; Compain, Philippe


Book ID
120417417
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
524 KB
Volume
78
Category
Article
ISSN
0022-3263

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✍ G Madhusudhan; G Om Reddy; J Ramanatham; P.K Dubey 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 124 KB

Ethyl anti-4-substituted phenyl-2-oxo-1,3-oxazolidine-5-carboxylates were synthesized stereoselectively in excellent yields using the Ph 3 P-CCl 4 -Et 3 N system by S N 2 cyclization of N-Boc-b-amino alcohols. syn to anti conversion of ethyl 4-substituted phenyl-2-oxo-1,3-oxazolidine-5-carboxylates