✦ LIBER ✦

Synthesis of 4-Hydroxycoumarin and 2,4-Quinolinediol Derivatives and Evaluation of Their Effects on the Viability of HepG2 Cells ad Human Hepatocytes Culture.

✍ Scribed by Bernard Refouvelet; et al. et al.

Publisher: John Wiley and Sons
Year: 2005
Weight: 19 KB
Volume: 36
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200511148

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis and Evaluation of the β-Turn P

Synthesis and Evaluation of the β-Turn Properties of 4-Amino-1,2,4,5-tetrahydro-2-benzazepin-3-ones and of Their Spirocyclic Derivative

✍ Karolien Van Rompaey; Steven Ballet; Csaba Tömböly; Rien De Wachter; Kenno Vanom 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 246 KB

## Abstract A series of 4‐amino‐tetrahydro‐2‐benzazepin‐3‐one derivatives (Ac–Aba–Xxx–NHMe) were prepared as tetrapeptide mimetics. Considering the structural resemblance with the so‐called Freidinger lactams, their propensity to adopt a β‐turn conformation was investigated by NMR spectroscopy (sol

Effect of silybin and its glycosides on

Effect of silybin and its glycosides on the expression of cytochromes P450 1A2 and 3A4 in primary cultures of human hepatocytes

✍ Pavel Kosina; Patrick Maurel; Jitka Ulrichová; Zdeněk Dvořák 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 203 KB 👁 1 views

## Abstract Four β‐glycosides of flavonoligan silybin, i.e. silybin β‐galactoside, silybin β‐glucoside, silybin β‐maltoside, silybin β‐lactoside were synthesized in order to improve silybin water solubility and bioavailability (Křen et al., J Chem Soc, Perkin Trans 1, 2467–2474, 1997). The presente

Synthesis and Effects on the COX-1 and C

Synthesis and Effects on the COX-1 and COX-2 Activity in Human Whole Blood ex vivo of Derivatives Containing the [1]Benzothienol-[3, 2-d]pyrimidin-4-one Heterocyclic System

✍ Andrea Santagati; Giuseppe Granata; Agostino Marrazzo; Maria Santagati 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 103 KB 👁 2 views

ChemInform Abstract: A Versatile Synthes

ChemInform Abstract: A Versatile Synthesis of Benzothieno-Anellated 1,2-Dihydropyridine and 1,2,3,4-Tetrahydropyridine Derivatives: The Effect of the Structure of Benzothieno-Anellated Pyridinium Salts on Their Reduction by Sodium Borohydride.

✍ Maksym A. Kryuchkov; Roman I. Zubatyuk; Igor F. Perepichka; Oleg V. Shishkin; Se 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 1 views

Comparison of the effects of the chemopr

Comparison of the effects of the chemopreventive agent resveratrol and its synthetic analog trans 3,4,5,4′-tetramethoxystilbene (DMU-212) on adenoma development in the ApcMin+ mouse and cyclooxygenase-2 in human-derived colon cancer cells

✍ Stewart Sale; Richard G. Tunstall; Ketan C. Ruparelia; Gerry A. Potter; William 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 306 KB 👁 1 views

## Abstract Naturally occurring molecules with putative cancer chemopreventive properties such as the phytoalexin resveratrol (3,5,4′‐trihydroxystilbene) are lead molecules that guide the design of novel agents with improved pharmacologic properties. The synthetic resveratrol analog 3,4,5,4′‐tetram

Synthesis and evaluation of novel N-subs

Synthesis and evaluation of novel N-substituted N′-(3-hydroxy-17-oxoestra-1,3,5(10)-trien-2- and -4-yl)thiourea derivatives for binding to the estrogen receptor and cytotoxic activity on mcf-7 cells

✍ A.-Mohsen M. E. Omar; Omaima M. Aboulwafa; G. Leclercq 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 350 KB 👁 1 views