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Synthesis of 4-carboxy-2,3-dihydrofuro(2,3-b)quinoline

✍ Scribed by P. Lakshminarayana; P. Shanmugam; K.K. Balasubramanian

Publisher: Elsevier Science
Year: 1970
Tongue: French
Weight: 97 KB
Volume: 11
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)89317-x

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✦ Synopsis

It has been observed' that J-(l'-propenyl)P-quinolonee readily yield 2-methyl-2,3-dihydrofuro(2,3-b)quinolines on treatment with polyphosphorio acid whereas 3-vinyl-2-quinolones do not afford the oorreeponding dihydrofuroquinolines under the same conditions2. In this communication, we report a novel synthesis of 4_carboxy-2,3dihydrofuro(2,3-b)quinoline (V), utilising the hitherto unknown 4-oarboq-3vinyl-2-quinolone (II) l-l r II-~_

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