Synthesis of 4- and 5-(s-triazolo[4,3-b]pyridazinyl-3)-substituted cyclic polyols
✍ Scribed by Cvetka Turk; Jury Svete; Amalija Golobič; Ljubo Golič; Branko Stanovnik
- Book ID
- 102339365
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1998
- Tongue
- English
- Weight
- 391 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
4(R)‐(6‐Chloro‐s‐triazolo[4,3‐b]pyridazinyl‐3)‐1,4‐furanoses 10 and 11, 5(R)‐(6‐chloro‐s‐triazolo[4,3‐b]pyridazinyl‐3)‐1,5‐pyranose 13, and 2(S),3(R)‐dihydro‐5‐(6‐chloro‐s‐triazolo[4,3‐b]pyridazinyl‐3)‐2,3‐O‐isopropylidenefuran (12) were prepared by cyclization of hydrazones 6–9 obtained from 6‐chloro‐3‐hydrazinopyridazine (1) and aldofuranoses 2, 3 and 4, and aldopyranose 5.
📜 SIMILAR VOLUMES
## Abstract Open‐chain __C__‐nucleosides, 1‐(__s__‐triazolo[4,3‐__x__]azinyl‐3)polyols 13–18 were prepared by one‐pot synthesis from hydrazinoazines 20a,c and various __D__‐aldoses 1–6. No protective groups were required for these transformations. 1‐(__s__‐Triazolo[4,3‐__b__]pyridazinyl‐3)‐__D__‐__
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