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Synthesis of 3β-(4-[125I]iodophenyl)tropane-2-β-pyrrolidine carboxamide ([125I]RTI-229)

✍ Scribed by Desong Zhong; Pravin Kotian; Christopher D. Wyrick; Herbert H. Seltzman; John A. Kepler; Michael J. Kuhar; John W. Boja; F. Ivy Carroll


Publisher
John Wiley and Sons
Year
1999
Tongue
French
Weight
275 KB
Volume
42
Category
Article
ISSN
0022-2135

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Binding of the [125I]3β-(Iodophenyl)trop
✍ Nian-Hang Chen; You-Lin Wang; Maarten E.A. Reith 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 123 KB 👁 1 views

The present study describes the binding of cocaine analog [ 125 I]3b-(iodophenyl)tropan-2b-carboxylic acid isopropyl ester ([ 125 I]RTI-121), a highly selective ligand for the dopamine transporter (DAT), to rat striatal synaptosomal membranes at 37°C. Saturation analysis of [ 125 I]RTI-121 binding r