Synthesis of 3,9-dimethylguanine and its conversion into 5-methyl-wye (Yt base), a model substance of wyosine, wybutosine and wybutoxine.

Synthesis of methyl [5,6,8,9,14,-3 H6]-h

Synthesis of methyl [5,6,8,9,14,-3 H6]-hepoxilin B3 and its conversion into methyl [5,6,8,9,14,15-3H6]-hepoxilin A3

✍ P. M. Demin; K. K. Pivnitsky; L. L. Vasiljeva; C. R. Pace-Asciak 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 462 KB

## Abstract The selective tritiation of methyl 10(R/S)‐hydroxy‐11(R),12(S)‐epoxyeicosa‐5,8,14‐triynoate into two C^10^‐epimeric [^3^H~6~]‐hepoxilins B~3~ methyl esters is described. These compounds are subsequently converted into two C^8^‐epimeric [^3^H~6~]‐hepoxilins A~3~ methyl esters by allylic