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Synthesis of 3,4-dihydropyrimidin-2(1H)-ones and 1,4-dihydropyridines using ammonium carbonate in water

✍ Scribed by Fatemeh Tamaddon; Zahra Razmi; Abbas Ali Jafari


Book ID
104097297
Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
272 KB
Volume
51
Category
Article
ISSN
0040-4039

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✦ Synopsis


Various known and new 3,4-dihydropyrimidin-2(1H)-ones and 1,4-dihydropyridines are prepared efficiently via Biginelli and Hantzsch reactions using ammonium carbonate in water. Competition between Biginelli and Hantzsch reactions is observed with pyridine carbaldehydes. Using this methodology, Hantzsch esters are synthesized in higher yields and purities than with other procedures without the use of a catalyst or an organic solvent.


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ChemInform Abstract: Synthesis of 3,4-Di
✍ Fatemeh Tamaddon; Zahra Razmi; Abbas Ali Jafari πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 33 KB πŸ‘ 1 views

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