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Synthesis of 3,4-dihydro-3,3-dimethyl-1(2H)-acridinone

✍ Scribed by Roberto Martínez; Georgina Espinosa-Pérez; Marco Brito-Arias


Publisher
Springer
Year
1995
Tongue
English
Weight
163 KB
Volume
25
Category
Article
ISSN
1572-8854

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Highly enantioselective reduction of 3,4-dihydro-2,2-dimethyl-2H-l-benzopyran-4-ones 3 s-e by BH3 was achieved in the presence of catalytic amounts of Corey's oxazaborolidine 4 to afford the corresponding 3,4-dihydro-2,2dimetbyl-2H-l-~nzopyran-4-ols 2a-e in quantitative yields. These benzopyran-4-ol