Synthesis of 3-Fluoro-Oxetane δ-Amino Acids
✍ Scribed by Lucas, Susana Dias; Rauter, Amelia Pilar; Schneider, Josef; Wessel, Hans Peter
- Book ID
- 126578573
- Publisher
- Taylor and Francis Group
- Year
- 2009
- Tongue
- English
- Weight
- 352 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0732-8303
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract (__R__)‐(−)‐2‐Amino‐4‐fluorobutyric acid (4c) (32% ee) and six of its homologues 9 have been synthesized by diastereoselective alkylation (54–72% yield) of (__R__)‐(+)‐camphor‐based glycine ester imines 1 with 1‐bromo‐2‐fluoro‐alkanes 6, at low temperature, followed by deprotection. Sim
Single-crystal X-ray study T = 93 K Mean '(C±C) = 0.001 A Ê R factor = 0.036 wR factor = 0.102 Data-to-parameter ratio = 12.2 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.