Synthesis of 3-aryl-5-styryl-2-pyrazolines by the reaction of (E,E)-cinnamylideneacetophenones with hydrazines and their oxidation into pyrazoles
✍ Scribed by Albert LÉvai; TamÁs Patonay; Artur M. S. Silva; Diana C. G. A. Pinto; José A. S. Cavaleiro
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2002
- Tongue
- English
- Weight
- 72 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
New 3‐aryl‐5‐styryl‐2‐pyrazolines have been synthesized by the reaction of (E,E)‐cinnamylideneace‐tophenones with hydrazines. These 2‐pyrazolines have also been converted into the corresponding pyrazoles by oxidation with chloranil. Structures of all new compounds have been elucidated by elemental analysis, mass spectrometry, ir and nmr spectroscopic measurements.
📜 SIMILAR VOLUMES
The reaction of dibenzylideneacetones or E,E-cinnamylidene-acetophenones and hydrazine hydrate provided 1-propionyl derivatives of 5-aryl-3-styryl-2-pyrazolines and 3-aryl-5-styryl-2-pyrazolines. These unsaturated ketones afforded 1-(2-carboxyphenyl) or 1-(4-carboxyphenyl) 5-aryl-3-styryl-2-pyrazoli
## Abstract New 4‐aryl‐2,3‐dihydro‐2‐styryl‐1,5‐benzothiazepines **8–13** have been synthesized by an acid catalyzed reaction of 2‐arninothiophenol (**1**) and (__E,E__)‐cinnamylideneacetophenones **2–7.** Ring contraction of 1,5‐benzothiazepines **8–13** provided 2,2‐disubstituted 3‐acetyl‐2,3‐dih