The preparation of enantiomerically pure 3,4-disubstituted glutamic acids is described starting from D-ribose. This preparation involved the use of a 2,3-aziridino-g-lactone whose reactivity towards nucleophiles could be efficiently controlled to allow selective functionalization at the b-position.
β¦ LIBER β¦
Synthesis of 3-Alkenyl-2-arylchromones and 2,3-Dialkenylchromones via Acid-Catalyzed Retro-Michael Ring Opening of 3-Acylchroman-4-ones.
β Scribed by David S. Clarke; Christopher D. Gabbutt; John D. Hepworth; B. Mark Heron
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 22 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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