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Synthesis of 3-(2-guanidinoethyl) and 3-[2-(S-methylisothioureidoethyl)] analogs of 5-isopropyl 2,6-dimethyl-1,4-dihydro-4-(2,3-dichlorophenyl)pyridine-3,5-dicarboxylate as a respective releaser of nitric oxide and inhibitor of nitric oxide synthase

โœ Scribed by Nadeem Iqbal; Edward E. Knaus


Book ID
112131442
Publisher
Journal of Heterocyclic Chemistry
Year
1996
Tongue
English
Weight
326 KB
Volume
33
Category
Article
ISSN
0022-152X

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Synthesis of Dialkyl 1,4-Dihydro-2,6-dim
โœ Raymond D. Anana; Edward E. Knaus ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 263 KB ๐Ÿ‘ 1 views

## Abstract The Hantzsch condensation of the heteroarylcarboxaldehydes 3aโ€c with alkyl acetoacetates 4aโ€c and alkyl 3โ€aminocrotonates 5aโ€b afforded the respective dialkyl 1,4โ€dihydroโ€2,6โ€dimethylโ€4โ€(heteroaryl)โ€pyridineโ€3,5โ€dicarboxylates 6aโ€f possessing a Cโ€4 4โ€quinolinyl, 8โ€quinolinyl or 1โ€oxidoโ€