Synthesis of 2H-1,3-oxazin-2-ones
β Scribed by Baydar, Ahmet E.; Boyd, Gerhard V.
- Book ID
- 121190100
- Publisher
- The Royal Society of Chemistry
- Year
- 1976
- Tongue
- English
- Weight
- 117 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-4936
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## Abstract Derivatives of the unknown 2βaminoβ6__H__β1,3βoxazinβ6βone **2** have been synthesized for the first time in two steps and in excellent yields, starting from __N__βcyanocarbonimidates **3a**β**c** and cyanoacetates. The structures of **2a**β**c** are assigned by NMRβspectroscopic method
The title compounds 4 were obtained on treatment of qanohydrines 3 of aliphatic and aryl aldehydes with oxalyl chloride or bromide in chlorobenzene at 9&C. Evidence for their structure is given by their spectroscopic data and by the Diels Alder reaction of 4a and & with acetylenic dienaphiles to yie