Synthesis of 25-oxygenated D:A-friedooleananes from D:A-friedoolean-7β -ol

✍ Scribed by Bhanusuta Mitra; Manju Sen; Saktipada Das

• Book ID: 104221808
• Publisher: Elsevier Science
• Year: 1988
• Tongue: French
• Weight: 127 KB
• Volume: 29
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)88490-7

✦ Synopsis

D:A-Friedoolean-25-01(l) and 25-al(2) have been synthesised from DzA-friedoolean-773 -01(i). SuTjstituted tetrahydrofuran rings are opened up on treatment with lithium in ethylenediamine to yield the corresponding saturated alcohols. Although a number of triterpenoids belonging to the D:A-friedooleanane group and containing oxygen functions at C-25 have been isolated

and their structures suggested l-7 , but none of these compounds has been synthasised or directly correlated with any known compound as yet. Some