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Synthesis of 2,5-dihalothiazole-4-carboxylates

✍ Scribed by John F Okonya; Fahad Al-Obeidi


Book ID
104251881
Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
84 KB
Volume
43
Category
Article
ISSN
0040-4039

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Synthesis of 1,2,4-triazines - XIV. Regi
✍ Tadashi Ohsumi; Hans Neunhoeffer πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science 🌐 French βš– 542 KB

Ethyl 1,2,4-triazine-5-carboxylates 6 were prepared by heating N,N-dimethylaminomethyleneor ethoxymethylenehydrazones 5 with ammonium acetate in acetic acid at-100Β°C. NMR-studies confirmed the absence of their regio isomers (6-carboxylates), showing the high regioselectivity of this procedure. Rece