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Synthesis of 2,4-substituted 3-oxo-1-phenylcyclopentane-1-carboxylic acids

✍ Scribed by A. O. Martirosyan; S. P. Gasparyan; V. E. Oganesyan; G. K. Arutyunyan; V. V. Martirosyan; M. V. Aleksanyan

Book ID: 111464181
Publisher: SP MAIK Nauka/Interperiodica
Year: 2006
Tongue: English
Weight: 170 KB
Volume: 42
Category: Article
ISSN: 1070-4280
DOI: 10.1134/s1070428006120050

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## Abstract Sulfonyl peptides containing a serine or threonine residue undergo cyclization with bis(succinimidyl) carbonate (DSC) and diisopropylethylamine (DIPEA) to give peptides with a 2‐oxo‐1,3‐oxazolidine‐4‐carboxylate (Oxd) group, either in solution or in the solid phase. The position of the