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Synthesis of 2,4-disubstituted pyrimido[4,5-b]-indoles, pyrano[4′,3′:4,5]pyrrolo[2,3-d]pyrimidines and some conversions of pyrimido[4,5-d]indoles

✍ Scribed by E. G. Paronikyan; A. S. Noravyan

Publisher
Springer US
Year
1996
Tongue
English
Weight
413 KB
Volume
32
Category
Article
ISSN
0009-3122

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Synthesis of pyrimido[4,5-b]indoles and
Synthesis of pyrimido[4,5-b]indoles and benzo[4,5]furo[2,3-d]pyrimidines via palladium-catalyzed intramolecular arylation
✍ Yue-Mei Zhang; Thomas Razler; Paul F. Jackson 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 305 KB

Various pyrimido[4,5-b] indoles and benzo [4,5]furo [2,3-d]pyrimidines were synthesized via a palladium-catalyzed intramolecular arylation of pyrimidine substrates. Thus, 4-aryloxy-or 4-anilino-5-iodopyrimidines were treated with Pd(OAc) 2 (PPh 3 ) 2 and base in DMF to give the regioselective cycli