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Synthesis of 2,3-diformyl-5-ethylbenzofuran and its derivatives

✍ Scribed by A. Prewysz-Kwinto


Book ID
112375663
Publisher
Springer US
Year
1982
Tongue
English
Weight
237 KB
Volume
18
Category
Article
ISSN
0009-3122

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The synthesis of 3,3-dimethylmorpholine-2,5-diones 4a was achieved conveniently via the direct amide cyclization of the linear precursors of type 3, which were prepared by coupling of 2,2-dimethyl-2H-azirin-3-amines 2 with 2-hydroxyalkanoic acids 1. Thionation of 4a with Lawessons reagent yielded th