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Synthesis of 2,2′-bipyridyl-type compounds via the suzuki-miyaura cross-coupling reaction

✍ Scribed by Nicholas A. Jones; James W. Antoon; Alfred L. Bowie Jr.; J. Brian Borak; Erland P. Stevens


Publisher
Journal of Heterocyclic Chemistry
Year
2007
Tongue
English
Weight
157 KB
Volume
44
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

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2,2′‐Bipyridyl‐type compounds may be prepared by Suzuki‐Miyaura coupling of a 2‐pyridylboronic ester with 2‐haloazines and ‐azoles. Ten examples are presented with yields of 47 to 84%. Both arylbromides and arylchlorides undergo the coupling, but the reaction is sensitive to ring substitution adjacent to the halogen.


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Synthesis of highly functionalized 2-(su
✍ Ramanatham Vinodkumar; Kotarkonda Rajagopal; Nayakanti Devanna 📂 Article 📅 2007 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 232 KB 👁 1 views

## Abstract magnified image A facile and convenient method for the synthesis of highly functionalized 2‐(substitutedbiphenyl) based benzimidazoles has been reported by the application of Suzuki‐Miyaura cross coupling reaction.