Synthesis of 2,2′-bipyridyl-type compounds via the suzuki-miyaura cross-coupling reaction
✍ Scribed by Nicholas A. Jones; James W. Antoon; Alfred L. Bowie Jr.; J. Brian Borak; Erland P. Stevens
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2007
- Tongue
- English
- Weight
- 157 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
magnified image
2,2′‐Bipyridyl‐type compounds may be prepared by Suzuki‐Miyaura coupling of a 2‐pyridylboronic ester with 2‐haloazines and ‐azoles. Ten examples are presented with yields of 47 to 84%. Both arylbromides and arylchlorides undergo the coupling, but the reaction is sensitive to ring substitution adjacent to the halogen.
📜 SIMILAR VOLUMES
## Abstract magnified image A facile and convenient method for the synthesis of highly functionalized 2‐(substitutedbiphenyl) based benzimidazoles has been reported by the application of Suzuki‐Miyaura cross coupling reaction.