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Synthesis of 21-esters of hydrocortisone with glycine and glutamic acid and study of their pharmacological activity

✍ Scribed by M. I. Ryakhovskaya; E. V. Popova; G. S. Grinenko; A. I. Terekhina; G. I. Gritsina; V. B. Nikitin; G. N. Engalycheva; M. É. Kaminka; R. G. Glushkov

Book ID
112404752
Publisher
Springer
Year
1990
Tongue
English
Weight
538 KB
Volume
24
Category
Article
ISSN
0091-150X

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## Abstract Homologation of the glutamic acid chain together with conformational constraint is a commonly used strategy to achieve selectivity towards different types of glutamate receptors. We investigated the effects of a further increase in the distance between the amino acid moiety and the dist