The first high yield synthesis is mported of 2-(aimethylsily1) a-D-mannopymnoside, using 2-0-benzoylated mannosy donors, as precursors. The success of the chemical synthesis of complex oligoaaccharides depends on the availability of monc+ and oligosaccharide building blocks that: 1. can dictate the
Synthesis of 2-(Trimethylsilyl)ethyl α-D-Mannopyranosides Revisited.
✍ Scribed by Rina Saksena; Jian Zhang; Pavol Kovac
- Book ID
- 101943351
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 158 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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During the preparation of simple mannopyranosides using the Koenigs-Knorr type reaction, we observed that a significant amount of disaccharide glycoside was produced when the alcohol was used in amounts less than equivalent of 2,3,4,6-tetra-O-acetyl-c~-D-mannopyranosyl bromide ("acetobromomannose").
## Abstract NMR experiments such as steady state NOE experiments and spin lattice ^1^H relaxation time measurements were performed on the synthetic disaccharide 10 that constitutes part of the polysaccharide backbone in fungal mannans. The spectro‐scopic data were compared with a theoretical model